Overview

This comprehensive suite of 12 tools is specifically designed for performing Analysis of Variance (ANOVA) on genomic data, including variant filtering, frequency analysis, and statistical testing.

Complete ANOVA Workflow

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Part C: Input Prep & ANOVA

  1. sql_query – Filter phenotype data with SQL
  2. id_conversion – Convert subject IDs and prepare phenotype table
  3. wes_id_mapping – Map phenotype IDs to WES column names
  4. rsids_for_genes – Extract rsIDs for gene lists
  5. filter_by_rsid – Filter variants by RSID list
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Part D: Filtering & Frequency Analysis

  1. filter_coding_variants – Filter variants to coding RSIDs only
  2. cohort_allele_freq – Compute cohort allele frequencies
  3. reference_allele_freq – Look up reference population frequencies
  4. freq_diff_topk – Select top frequency differences (two-sided)
  5. anova – Run ANOVA analysis per RSID (final step)

Workflow Diagram

ANOVA Study Workflow